Which of the following is true about antigen capture and presentation?
theck all that apply.
Cancer cells or virus infected cells that are not professional antigen
presenting cells do express costimulatory molecules and secrete
cytokines
Mature DC enhance antigen processing and presentation, upregulate
costimulatory and secrete cytokines for T cell activation
Mature DC recognizes antigen without PRR involvement and becomes
immature to process antigen and load on MHC to present on T cells
DCs not infected by viruses utilize cross presentation to be presented
by MHC I to CD8 T cells
Endogenously synthesized antigens are processed in proteasomes that
are transported by TAP to ER, loaded onto MHC I and presented to
CD8 T cells
Exogenous antigen endocytosed by APC are degraded to peptide in
endosomes and binds to MHC II after releasing CLIP and expressed on
cell surface to be presented to CD4 T cells