Which of the following mutations would most likely keep the transitions of T state to R state in hemoglobin unchanged, or similar to the transitions that occur in the native molecule? The three-letter codes for amino acids are used, and the numbers following the amino acids designate the amino acid position in the protein. By convention, the original, native amino acid is listed first, followed by the mutational change.
Choose one:
A. Asp94$\rightarrow$Glu94
B. Tyr42$\rightarrow$Gly42
C. Asp94$\rightarrow$Ile94
D. Tyr42$\rightarrow$Phe42