The blood-brain barrier (BBB) total length of cerebral blood vessels is ~400 miles long with capillaries contributing to 85% of the vessel length and providing ~12 m of the endothelial surface area available for transport exchanges. What is the primary function of this very extensive and complex system?
Group of answer choices
The BBB functions as an insulator around neurons.
The BBB functions as a sensor of infections.
The BBB prevents neurotoxic plasma components, blood cells, and pathogens from entering the brain.
The BBB prevents glucose from diffusing out of the brain.