When oxygen is low (hypoxia) for a long period of time, but glucose is available, the situation can lead to sepsis, and heart failure if the lactic acid builds up (Cori cycle is saturated). What is the metabolic cause?
P.S.: Your answer must include the correct metabolic pathway regulation in an hypoxia situation.
Question 6 options:
A)
Glycolysis is active, but the pyruvate oxidation and the Krebs cycle (citric acid cycle, tricarboxylic acid (TCA) cycle) are not operating at optimum speed.
B)
Glycolysis and pyruvate oxidation are active, but the Krebs cycle (citric acid cycle, tricarboxylic acid (TCA) cycle) is not operating at optimum speed.
C)
None of the answers proposed in the multiple-choice question are correct.
D)
Glycolysis, pyruvate oxidation and Krebs cycle (citric acid cycle, tricarboxylic acid (TCA) cycle) are operating at optimum speed.