- Describe the importance of pyruvate oxidation in the production of chemical energy (ATP) – if pyruvate oxidation does not occur, will cells have ATP?
- Describe the importance of the Krebs cycle (also known as the Citric Acid Cycle) in the production of chemical energy (ATP) – if the Krebs cycle does not occur, will cells have ATP?
- Given the Krebs cycle, develop a scientific experiment to determine the defect in the series of chemical reactions (a defect could be the inhibition of an enzyme, genetic defects leading to enzyme malfunction, removal of a substrate, etc).
- Describe the importance of oxidative phosphorylation in the production of chemical energy (ATP) – if oxidative phosphorylation does not occur, will cells have ATP? If the electron transport chain does not occur, will cells have ATP? If chemiosmosis does not occur, will cells have ATP?
- Explain the role of the two parts of oxidative phosphorylation and how they are dependent on one another.
- Discuss the mechanism of electron transfer that occurs in the electron transport chain.
- Compare the chemical properties of the different proteins found in oxidative phosphorylation – what type of amino acids would be found on the outside surfaces of these different proteins?
- Discuss the role of oxygen in aerobic respiration. In general, can organisms still respire (make ATP) if they are not able to metabolize oxygen (such as obligate anaerobes)?
- Explain the impact of 2,4-dinitrophenol (DNP) on cellular respiration.