MITOSIS PROBLEM
(a) Draw a picture of a diploid cell that has a genome consisting of TWO chromosomes
called Chr1 and Chr2.
(b) Draw a picture of your cell with its chromosomes through the 4 stages of mitosis:
prophase, metaphase, anaphase, telophase. At the end you should have two diploid
cells.
(c) Are these two cells you have created genetically identical?
(d) Go back to your drawing in part B and on the metaphase diagram, label the
metaphase plate, the centromeres, the centrosomes, the telomeres, the spindle.
(e) Which cytoskeleton proteins are involved insetting up the spindle? Which are
involved in cytokinesis? Where is the kinetochore? Which cytoskeletal component
associates with the kinetochore?
(f) What would happen during mitosis if the centromere was deleted from a
chromosome?
(g) What would happen during mitosis if one chromosome had TWO centromeres?
MEIOSIS PROBLEM.
(a) Draw a picture of a diploid cell that has a genome consisting of TWO chromosomes
called Chr1 and Chr2.
(b) Draw the 4 stages of Meiosis I. On the metaphase diagram, label the metaphase
plate, the centromeres, the centrosomes, the telomeres, the spindle.
(c) Why is Prophase I so important?
(d) You should now have TWO cells ready to go through Meiosis II. Draw the 4 stages
of Meiosis II. At the end, are all four cells genetically identical? Why?
(e) What are the differences between Metaphase I and Metaphase II in Meiosis?
(f) How does Metaphase I in Meiosis differ from Metaphase in Mitosis?
(g) Which is more like Mitosis, Meiosis I or Meiosis II?