There are many variations in cat color patterns encoded by different genes. The agouti phenotype (banded hair) is seen in cats with the dominant allele of the ASIP gene (A, agouti-signaling protein). The alternate, recessive ASIP allele leads to non-agouti phenotype (a, plain color).
The “wide-banded” version of the agouti phenotype is seen in cats with a dominant allele in the Wideband gene (W). This pattern “pushes” the tabby pattern out on the hair, removing most or all of the pattern. The alternate, recessive allele leads to the normal agouti phenotype (w).
A true-breeding cat with the agouti pattern and wide-banding is bred to a true-breeding cat without the agouti pattern (or wide-banding) to produce the F1 generation.
Draw all four of the potential gametes produced by an F1 cat. Specifically, draw cells with 2 of the autosomes (fewer than the reality, 18!). One of these chromosomes should have the linked genes, agouti and Wideband, which have a 30% recombination rate. Assume that the chromosomes that do not contain the agouti and Wideband genes are homozygous and do not lead to a phenotype we are interested in. Indicate which gametes are parental and which are recombinant
What is the expected frequency of each gamete? Show your work. (0.5 pt)
Redraw the non-recombinant gametes. Color the chromosomes in this way: use red for chromosomes in the gamete that contains the dominant wide-banded and agouti alleles. Use blue for the chromosomes in the other gamete. Imagine these gametes combined to create an F2 cat. Show a cell of this cat after mitosis in G1 with the genes labeled with the correct alleles and the chromosomes colored based on which parent they came from.
A cell from this cat has undergone meiosis I. Draw the resulting cells and include a single recombination event between the agouti and Wideband genes. Be sure to label the alleles and color the chromosomes based on which parent they came from. (1.5 pt)
Both of the cells in (d) continued through meiosis II. Draw the resulting cells. Be sure to label the alleles and color the chromosomes based on which parent they came from. (1.5 pt)