Q1 Analyze and Discuss. 1. Arthur, Bridget and their three children Charles, Daniel and Eliza were typed for their HLA-A, HLA-B and DR loci. The results were: Arthur A3,23 ; B 7,27 ; DR 3,4. Bridget A2,23 ; B 15,27 ; DR 3,4. Charles A3,23 ; B 15,27 ; DR 3,4. Daniel A2,23 ; B 7,27 ; DR 3,4. Eliza A2,3 ; B27 ; DR 4. Assuming there is no recombination, so that a persons A, B, DR alleles are passed an unbroken haplotype, work out the haplotypes in this family. Who do you think has the best tissue match. (hint: Eliza is homozygous for B27 and DR 4.