1400
[?] Hint
Question 4 of 4
Observe the sequencing data comparing a wild type and a Tay-Sachs individual.
Normal HEXA allele
q, Arg q,
q, Ile Ser q, Tyr q,
q, Pro q, Asp q, ...
. . CGT ATA
TCC
TAT
GCC
CCT
GAC . . .
Tay-Sachs allele
... CGT
ATA
TCT
ATC
CTA
TGC
cCc
TGA
C...
Identify the changes that describe the Tay-Sachs mutation.
substitution
nonsense
frameshift
insertion
inversion