Texts: Please indicate whether the following statements are true or false given the prompt.
A. Gal4 will be expressed but it will not activate GFP in any of the somatic cells without heat shock.
B. After heat shock, FLP recombinase will be induced, which will induce mitotic recombination at the FRT40A location, resulting in the generation of clones of cells with homozygous hrb27c mutation and homozygous P{Tub-Gal80} insertion.
C. After heat shock, FLP recombinase will be induced, which will induce mitotic recombination at the FRT40A location. However, hrb27c mutant clone will not be generated because FRT40 and hrb27c mutation are located on different chromosome arms.
D. After heat shock, the hrb27c mutant clones generated can be identified by the absence of GFP expression.
E. hpo (hippo) mutant clones and the corresponding WT twin spots were generated during Drosophila eye development, determine whether the following statements are true or false:
A. hpo mutant clones will be larger than twin spots with more cells.
B. hpo mutant clones will be larger than twin spots with larger cells.
C. bpo mutant clones will be larger than twin spots with high levels of phosphorylated Wts.
D. bpo mutant clones will be larger than twin spots with high levels of phosphorylated Yki.
gigas (gig, fly TSc2) mutant clones and the corresponding WT twin spots were generated during Drosophila eye development, determine whether the following statements are true or false:
A. gig mutant clones will be larger than twin spots with larger cells.
B. gig mutant clones will be larger than twin spots with more cells.
C. gig mutant clones will be larger than twin spots with high levels of phosphorylated Akt.
True or false about the following statements on Drosophila eye development:
A. Hh, which is expressed by the developing photoreceptors in the anterior eye disc, induces cells in the morphogenetic furrow (MF) to express DPP, which is the ligand of DPP (BMP) signaling.
B. Wg and Notch signaling inhibit while Hh and DPP signaling promote the co-expression of RD genes including Ey (Eyeless) and Eya (Eyes absent) in the preproneural (PPN) domain anterior to the MF.
C. Co-expression of the retinal determination (RD) network genes Eya (Eyes absent), sine oculis (so), and Ey (Eyeless), which is observed in PPD.
D. While EGFR signaling is not required for R8 specification, EGFR signaling is required for cell survival in posterior eye discs and for the differentiation of all the remaining cell types in the ommatidia.
E. During Drosophila eye development, cell proliferation in the second mitotic wave is required for the differentiation of different cell types.
