urces can be used. Any usage of non-course materials will be treated as a ho
e violation. Thanks for taking BIO 480 this summer!
d Luck!
Question 25
2 pts
Use the below Multiomics mouse retina data (DNasel-seq, CRX and
NRL transcription factor ChIP-seq) to answer the following question
about the mouse RHO gene.
mm9
2 kb
115,887,000 115,886,000 115,885,000 115,884,000 115,883,000 115,882,000 115,881,000
WT Retina CRX Binding Regions
WT Retina NRL Binding Regions rep1
UCSC Genes (RefSeq, GenBank, tRNAs & Comparative Genomics)
Retina Newbom 1 Day DNasel HS Signal Rep 1 from ENCODE/UW
Retina Adult 1 week DNasel HS Signal Rep 1 from ENCODE/UW
Retina Adult 8 Weeks DNasel HS Signal Rep 1 from ENCODE/UW
Placental Mammal Basewise Conservation by PhyloP
Multiz Alignments of 30 Vertebrates
Rho
Scale
chr6
wt CBRs
WT NBR rep1
Retina N1d S 1
Retina A1w S 1
Retina A8w S
Mammal Cons
Cow
Chicken
(True/False) The data shown for this region confirms that NRL and
CRX bind to the exact same DNA sequences.
O Trué
• False
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