Question 6 of 10
© Macmillan Learning
Protein A has a binding site for ligand X with a dissociation constant, $$K_d$$, of $$3.0 \times 10^{-7}$$ M. Protein B has a binding site for ligand X with a $$K_d$$ of $$4.0 \times 10^{-8}$$ M.
Calculate the $$K_a$$ for each protein.
Protein A $$K_a$$ =
Protein B $$K_a$$ =
$$M^{-1}$$
$$M^{-1}$$
Which protein has greater affinity for ligand X? Why?
Protein B has greater affinity because it has a lower $$K_d$$ than Protein A.
Protein B has greater affinity because it has a greater $$K_a$$ than Protein B.
Protein A has greater affinity because it has a greater $$K_a$$ than Protein A.
Protein B has greater affinity because it has a lower $$K_d$$ than Protein B.
Protein A has greater affinity because it has a greater $$K_d$$ than Protein B.
