Artibodies and Tests for Their Presence
1. Distinguish between antigen and antibody.
2. Describe the four protein chains that make up the immunoglobulin monomer, and draw a typical model in the box below. Label the variable regions and constant regions.
3. In the Ouchterlony test, what happens when the antibody to horse serum albumin is mixed with horse serum albumin?
4. If the unknown antigen contained bovine and swine serum albumin, what would you expect to happen in the Ouchterlony test, and why?
Lymphedema is a condition characterized by insufficient movement of lymph in the lymphatic vessels. Fluid builds up in the tissues and in the lymphatic vessels of the limbs. Explain why exercise would have a positive effect on this condition.
Buboes are a key sign for diagnosing bubonic plague. Buboes are swollen lymph nodes that can become necrotic and turn black. Predict where on the body buboes would be most likely to develop in cases of the bubonic plague.