All are correct statements regarding the protein degradation process involving ubiquitin EXCEPT: a. The ubiquitin is covalently attached to a cysteine residue in the protein to be degraded. b. Three additional proteins (E1, E2, and E3) are involved in the ligation of ubiquitin to the protein. c. The ubiquitin binding to the protein to be degraded leads to a novel branched protein. d. The modified protein is degraded by an ATP-dependent protease complex. e. Ubiquitin is a highly conserved protein. 2. Which of the following is a result of the sumoylation of a protein? a. Addition of SUMO targets a protein for destruction by a slightly different pathway than attachment of ubiquitin. b. Addition of SUMO often changes the conformation of a protein so that it interacts with other proteins in a different manner. c. Addition of SUMO targets a protein for transport into the mitochondria. d. The addition of SUMO occurs during the translation process and is meant to stall translation of certain proteins. e. None of the above.
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The incorrect statement regarding the protein degradation process involving ubiquitin is: a. The ubiquitin is covalently attached to a cysteine residue in the protein to be degraded. In fact, ubiquitin is typically attached to a lysine residue in the protein to be Show more…
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