1. Cancer cells reactivate which enzyme involved in DNA replication? Group of answer choices: helicase RNAse H telomerase DNA ligase DNA polymerase 2. How many fatty acid molecules are in each sphingolipid? Group of answer choices: 1 or 2 2 1 3 0 3. Which of the following proteins is not a functional part of the secretory vesicle? Group of answer choices: v-SNARE GTP-binding proteins coat protein t-SNARE cargo-receptor 4. Which of the following is found specifically in muscle but not other tissues? Group of answer choices: neurofilament vimentin keratin lamin desmin 5. Proteins do NOT require a signal sequence to enter which of the following cellular compartments? Group of answer choices: mitochondria cytosol endoplasmic reticulum nucleus peroxisome 6. The Tom protein acts on proteins destined for which cellular location? Group of answer choices: cytosol endoplasmic reticulum mitochondria nucleus peroxisome 7. The KDEL sequence in proteins signals what type of vesicular transport: endocytosis anterograde Golgi to endoplasmic reticulum trans-Golgi to lysosome trans-Golgi to plasma membrane
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1. Which of the following would be synthesized on the rough endoplasmic reticulum and pass through the Golgi apparatus? (Think about where the proteins function, and how proteins are targeted to that location.) A) mitochondrial enzymes encoded in the nucleus B) cytosolic proteins C) secreted proteins D) DNA polymerase and RNA polymerase 2. Ubiquinone (CoQ) and plastoquinone (Pq) A) are water soluble B) move protons across a membrane as they shuttle electrons C) are large protein complexes D) are located in the same membrane of the same organelle 3. for a protein to enter the nucleus it must A) contain an internal nuclear localization signal B) first be unfolded C) be translated in the nucleus D) be transported co-translationally in the ER
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Of the following organelles, which group is involved in manufacturing substances needed by the cell? a. lysosome, vacuole, ribosome b. ribosome, rough ER, smooth ER c. vacuole, rough ER, smooth ER d. smooth ER, ribosome, vacuole e. rough ER, lysosome, vacuole 2. Which of the following is NOT a characteristic of prokaryotes? a. DNA b. cell membrane c. cell wall d. endoplasmic reticulum 3. Proteins synthesized by the rough ER are: a. for internal storage in the Golgi Apparatus b. to build more membranes in the cell c. to digest food in lysosomes d. for internal regulation e. exported from the cell 4. Which of the following describes the fluid-mosaic model of the plasma membrane structure? a. phospholipid monolayer with embedded proteins b. phospholipid bilayer with embedded proteins c. phospholipid trilayer with embedded proteins d. triglyceride bilayer with embedded proteins e. triglyceride monolayer with embedded proteins 5. True (a) or False (b): Metabolism is a complex chemical process accomplished in an organism by which large molecules are destroyed and small ones are produced. At the end of this process, composed of 2 different kinds of reactions (catabolism and anabolism), energy is produced and released by cells.
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Questions $94-96$ A tissue or cells can be mashed up in a blender to form a liquid homogenate and then spun in an ultracentrifuge at high speeds to separate it into layers based on differences in density. The densest cell organelles settle to the bottom of the tube, forming a pellet. The supernatant, the liquid above the pellet, which contains less-dense organelles, can be poured off and respun. In this way, cell organelles can be isolated. A homogenate of human tissue was processed and spun in this way. See the diagram below. Pellet $\mathrm{B}$ was found to have the highest rate of oxygen uptake compared with the other pellets. Which organelles did it contain? (A) Ribosomes (B) Mitochondria (C) Vacuoles (D) Golgi (E) Nuclei
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Biology E/M Sample Test 2
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