1. Check all the correct statements about the cell cycle.
During the G2 checkpoint in eukaryotic cells, the cell is
assessed with regard to DNA replication.
During the M checkpoint in eukaryotic cells, the cell
is assessed with regard to chromosomal attachment at the
spindle..
Among, G1, S, G2 and M phases, G1 is the most
variable phase.
In normal cells, apoptosis happens during G1 phase.
2. Phosphorylation of target proteins by CDKs and
dephosphorylation by protein phosphatases is a common mechanism for
controlling the cell cycle. Which of the
following are accurate examples of
CDK dependent activation?
Phosphorylated lamin proteins causes lamina breakdown and
destabilization of the nuclear envelope during prophase
Activation of the anaphase-promoting complex (APC),
a ubiquitin ligase
Phosphorylation of Receptor Tyrosine Kinase leading to cell
proliferation
Phosphorylated condensins cause chromosome
condensation
Phosphorylation of Rb protein and activation of gene
transcription