During nucleotide excision repair (NER), which of the following is true? a) removal of uracil base from the DNA strand b) recognition of the DNA distortion by the UvrAB complex c) unwinding of sister chromatid which is used as a template for the damaged strand d) hemi-methylated DNA is used to determine the correct base 2. Which are examples of damage found in DNA? a) phosphodiester strand breaks due to X-rays b) thymine-thymine dimers formed by UV radiation c) deamination of cytosine to uracil d) alkylating agents modifying a guanine
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During nucleotide excision repair (NER), the correct statement is: b) recognition of the DNA distortion by the UvrAB complex Show more…
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What aspect of DNA structure makes it possible for the enzymes of nucleotide excision repair to recognize many different types of DNA damage? a. the polarity of each DNA strand b. the antiparallel orientation of strands in the double helix c. the energy differences between correct and incorrect base pairs d. the regularity of DNA's overall structure
Which of the following statements about excision repair is correct? a. Base excision repair is initiated by DNA glycosylases that recognize abnormal deoxyriboses in DNA. b. Nucleotide excision repair removes large regions of DNA via an excinuclease which cuts on either side of the damaged bases. c. E. coli exonuclease activity is carried out by uvrA, uvrB, and uvrC, and the resulting gap is filled in by DNA Pol III. d. DNA glycosylases cleave the altered nucleoside (base and sugar) from the DNA backbone, creating an apurinic or apyrimidinic site. e. In humans, a mechanism similar to E. coli is carried out where the protein XPA acts as the exonuclease.
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1) The products of DNA replication are two DNA molecules. Which of the following statements about these two DNA molecules is false? a) they are sister chromatids b) they are both double-stranded DNA helices c) they carry different sets of gene alleles d) they each consist of one "old" strand, which was the template strand, and one "new" strand, which was just synthesized 2) In which of the following molecular processes is the formation of Watson-Crick type base pairs between DNA or RNA polynucleotides NOT critical to the mechanism? a) PCR b) transcription c) DNA replication d) no good answer - all of these depend to some degree upon base pairing interactions e) translation d) taking apart the nuclear membrane
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