If there were a high allele frequency for the CCR5-32 coreceptor, and the rate of infection with HIV was high as well, one would expect the frequency of the CCR5-32 coreceptor allele to ______ a) fall quickly due to heterozygote selection b) remain the same due to the population maintaining Hardy-Weinberg equilibrium c) rise quickly and confer resistance on a large part of the population d) remain the same due to the lethality of AIDS 2. Under the Neutral Theory, if an allele frequency in a population is 0.7 -- what is the probability that it will become fixed (100% in the population)? a) it depends on the population size b) 0.3 c) more than 0.7 d) it is random e) 0.7 3. When selection for diversity in favoring a part of the genome (like Major Histocompatibility Complex Variation): a) the accumulation of non-synonymous mutations should be less than synonymous mutations b) the accumulation of non-synonymous mutations should be greater than synonymous mutations c) the accumulation of non-synonymous mutations should be equal to synonymous mutations
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The CCR5-32 coreceptor allele is known to provide resistance to HIV infection. Therefore, if there were a high allele frequency for the CCR5-32 coreceptor and the rate of HIV infection was high as well, one would expect the frequency of the CCR5-32 coreceptor Show more…
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A mutation has occurred in an animal population so that the homozygous recessive condition (ff) results in a fatal disease for the animal. Affected individuals die soon after birth. The homozygous dominant (FF) and the heterozygous (Ff) individuals live normally. A study of the population over one year found that 4% of the newborn individuals died soon after birth. An equal number of males and females died. Using a Punnett square and the Hardy-Weinberg Principle, calculate the frequencies of the alleles in the new generation. Then answer the questions that follow. a. Assume that 100 individuals were born in the animal population. How many of these 100 animals would probably be carriers (heterozygous) of the allele for the recessive trait? b. How many of these 100 animals would not carry the allele for the recessive trait? c. Assume that the 96 surviving individuals of the new generation become a new breeding population. What is the total combined number of the two alleles in the breeding population? d. How many of these alleles are for the dominant condition? e. How many of these alleles are for the recessive condition? f. What is the frequency of the allele for the dominant condition in the new breeding population? g. What is the frequency of the allele for the recessive condition in the new breeding population? h. What happened to the allele frequencies in a single generation? i. Selection is operating against which allele? j. If this situation were to continue for several generations, what would be the result? k. Lethal recessive genes never disappear from a population. Why?
Madhur L.
POPULATION GENETICS 10. If p is the frequency of B allele and q is the frequency of the b allele, which of the following indicates the frequency of individuals who are heterozygous in a population at Hardy-Weinberg equilibrium? A. p² B. q² C. p² + 2pq + q² D. 2pq E. p² + 2pq 11. Earwax type is determined by two alleles of the ABCC11 gene: the ABCC11ᴬ allele is recessive and results in dry earwax while the ABCC11ᴳ allele is dominant and produces wet earwax. In a population that is at Hardy-Weinberg equilibrium for this gene, 91% of people have wet earwax. What is the frequency of the ABCC11ᴳ allele in the population? A. 0.30 B. 0.09 C. 0.49 D. 0.91 E. 0.70 12. A dominant and a recessive allele of a single locus are at equal frequencies in a large population, initially at Hardy-Weinberg equilibrium. The population is reduced in a single generation to less than 50 individuals and remains at this size for many more generations. What is the MOST LIKELY consequence of the smaller population size? A. The recessive allele will be lost from the population. B. One of the two alleles will be lost from the population—it could be either the dominant or the recessive allele. C. Both alleles will remain at the same frequencies as before. D. The dominant allele will be lost from the population. 13. Which of the following will NOT, by itself, affect the frequency of an allele in a population over time? A. Whether the size of the population is small. B. Whether the allele is dominant or recessive. C. Whether the allele is subject to selection. D. Whether the allele is subject to mutation at a high rate. E. Whether there is migration from another population lacking the allele.
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Each of two isolated populations is in Hardy-Weinberg equilibrium with the following genotype frequencies: $$\begin{array}{llll} \text { Genotype: } & A A & A a & a a \\ \text { Frequency in Population 1: } & 0.04 & 0.32 & 0.64 \\ \text { Frequency in Population 2: } & 0.64 & 0.32 & 0.04 \end{array}$$ (a) If the populations are equal in size and they merge to form a single large population, predict the allele and genotype frequencies in the large population immediately after merger. (b) If the merged population reproduces by random mating, predict the genotype frequencies in the next generation. (c) If the merged population continues to reproduce by random mating, will these genotype frequencies remain constant?
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