00:01
Hello student here the question is given and the question is about the muscle contraction mechanism.
00:07
So in the case of muscle contraction, we know the atp are used.
00:13
So atp used in which process and why it is used.
00:19
So we know this atp is used when myocene head undergoes conformational change.
00:35
Changes, conformational changes.
00:42
So we know when the contraction occurred, the muscle fiber is getting stimulus.
00:49
So suppose the stimulus is received by the muscles.
00:54
So by receiving the stimulus, there are release of calcium ion from the sarcoplasmic end of reticulum or sarcoplasmic which is a specialized type of endoplasmic reticulum so these calcium iron is going to bind with the proponine and binding of calcium with the troponine lead to the conformational changes and the expose of these myocene binding side in the actin filament so if you look at this a structure here these diagram represents this is the actin filament so this filament is actin filament or filament so this mainly made by the troponine and tropomyosine so whenever these calcium bind to the troponin these conformational changes will take place and these myosine binding side in this thin filament is exposed and these myosine head has come and bind to this myosin binding side on the actin filament so during this binding the atp hydrolysis will take place and the release of inorganic phosphate and atp will be takes place and so this is due to the atp hydrolysis so here adp and inorganic phosphate released by the miocene wed wind bind and this ultimately lead to this power stroke so this power stroke is mainly the release of adp and inorganic phosphate so the movement of these thin filament inside the this inside the sarcomere so toward the sarcomere so it ultimately lead to the sort in the muscle fiber so this is going to lead to the certain the muscle fiber because it is moving inward so here the muscle fiber is going getting shorter so this is a case of sliding filament theory so here the actin filament is moving inside and and this is mainly due to the release of these adp and inorganic phosphate.
03:09
And it is by this atp hydrolysis.
03:12
And whenever these atp bind to this myocene, this is going to be detached from these myosine binding side.
03:22
So this atp binding further detachment of these myosine head require.
03:28
And after detachment, this is the cocking of myosine head will be takes place.
03:34
So it is an original state like the previous one.
03:38
And whenever these myosine binding site exposed at this thin filament, they comes and bind and these mechanisms start again for the muscle contraction.
03:50
So this is the muscle contraction and the atp utilize for the myosine head whenever they undergo conformational changes...