00:03
A signal peptide is an enzyme that stay in er, which cleaves the signal peptide sequence of the protein is located in, translocated in er.
00:12
First of all, do you think the signal peptides will be synthesized with a signal peptide? the first question, the answer is yes.
00:20
So when you have a polypeptide from n to c, if there's no signal peptide, usually it's by default as a cytoplasmic protein.
00:30
So they will stay inside a plasm.
00:34
Now, if a protein is located in some other compartments such as nuclear, plasma membrane, or er, they definitely have a signal sequence which would direct them to the compartment that they belong.
00:47
And usually the signal sequence is at the end terminus, but sometimes it can be at the c terminus.
00:52
So you can see, this is a signal peptide, and this is the regular sequence from n to c.
01:01
So the red portion is the signal peptide.
01:05
So signal peptide usually has its unique feature, so it's basically a address label.
01:15
And it will tell the polypeptide to go to its compartment that it belongs.
01:21
So in this case, a signal peptide is located in er...