Question

Q1. The amino acid Tyrosine has pKa values 2.2, 9.1 and 10.1. (a) Show the stepwise ionization of tyrosine as a function of pH. (b) At what pH tyrosine exists as Zwitterionic form? (c) At what pH tyrosine solution has a net – 2 charge? (d) What is the pH of a tyrosine solution in which the ??–amine group is 40% deprotonated? (show calculation!)

          Q1. The amino acid Tyrosine has pKa values 2.2, 9.1 and 10.1.

(a) Show the stepwise ionization of tyrosine as a function of pH.
(b) At what pH tyrosine exists as Zwitterionic form?
(c) At what pH tyrosine solution has a net – 2 charge?
(d) What is the pH of a tyrosine solution in which the ??–amine group is 40% deprotonated? (show calculation!)

Q1. The amino acid Tyrosine has pKa values 2.2, 9.1 and 10.1.

(a) Show the stepwise ionization of tyrosine as a function of pH.
(b) At what pH tyrosine exists as Zwitterionic form?
(c) At what pH tyrosine solution has a net – 2 charge?
(d) What is the pH of a tyrosine solution in which the ??–amine group is 40% deprotonated? (show calculation!)

Added by Sofia G.

Biology for AP Courses

Julianne Zedalis, John Eggebrecht

Instant Answer

Solved by Expert Adi S

09/09/2023

Step 1

Stepwise ionization of tyrosine as a function of pH: At low pH (below 2.2), tyrosine is fully protonated: $$\mathrm{NH_3^+CH_2CH(OH)COOH}$$ Between pH 2.2 and 9.0, the carboxyl group loses a proton: $$\mathrm{NH_3^+CH_2CH(OH)COO^-}$$ Above pH 9.0, the amino Show more…

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Q1. The amino acid Tyrosine has pKa values 2.2, 9.1 and 10.1. (a) Show the stepwise ionization of tyrosine as a function of pH. (b) At what pH tyrosine exists as Zwitterionic form? (c) At what pH tyrosine solution has a net - 2 charge? (d) What is the pH of a tyrosine solution in which the ̑̑-amine group is 40% deprotonated? (show calculation!)