1a) Why microtubules are called polar filaments? What is the basis for this polarity? How is polarity related to microtubule organization within the cell, and how is polarity related to the intracellular movements powered by microtubule-dependent motors? 1b) What are intermediate filaments? Describe in detail the structural organization of intermediate filaments. 1c) Explain with suitable schematic the regulation of eukaryotic cell cycle at G1/S transition.
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This polarity is based on the arrangement of alpha and beta tubulin heterodimers that make up the microtubule structure. Show more…
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Microtubules are polar filaments; that is, one end is different from the other. What is the basis for this polarity, how is polarity related to microtubule organization within the cell, and how is polarity related to the intracellular movements powered by microtubule-dependent motors?
Classify each characteristic based on whether it describes actin filaments, intermediate filaments, and/or microtubules. Some characteristics may apply to more than one category. Primarily associated with movement Involved in cell division Protein composition varies from cell to cell Take part in formation of cell-to-cell junctions Support the plasma membrane Act as tracks along which organelles can move Short, cylindrical structures composed of 13 rows of tubulin Colchicine binds these fibers to block cell division The proteins of this fiber interact with myosin during muscle contraction Support the nuclear envelope Actin filaments Intermediate filaments Microtubules
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