1)If there are errors in the primary structure of a polypeptide
that negatively impact function, which is the most likely
reason?
Alterations in the type of bonds formed between the polypeptide
backbone
Alterations in the secondary structure with tertiary structure
will remain intact.
Alterations in the secondary and tertiary structure
Alterations in the tertiary structure
2) Based on what you know about protein structure and function,
why do you predict a prolonged high fever can be fatal if left
untreated?
Proteins will become denatured, causing them to unravel and lose
their secondary and tertiary structure leading to a loss of their
important biological functions.
Proteins will fold together even more compactly due to the
excessive heat causing alterations in their three-dimensional shape
and therefore altering their important biological functions.
The high temperature breaks the peptide bonds holding the
proteins together causing them to become degraded and unable to
perform their important biological functions.
The high temperature causes the cell to lose water, and since
all proteins are hydrophilic they won’t be able to function
properly.