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Hello, students.
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Now, in this question, they're asking regulated metabolic pathways are irreversible, committed after the first step, usually regulated at the first step, compartmentalized in eukaryotes, all are correct.
00:15
In this case, what we need to understand is what is this regulation of a metabolic pathway? what does that mean? see, in case of metabolic pathways, let us consider the best example and always use example that is the glycolysis.
00:30
In glycolysis what basically happens is that the glucose that is present is basically converted to glucose 6 phosphate right.
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After the glucose 6 phosphate is formed it is converted to fructose 6 phosphate and then you will observe fructose 1 6 phosphate to be formed.
00:49
So here if we observe the regulatory step that is present here is this particular step and this particular step, right? so here you will observe that regulation is occurring at the first step, which means that it is fixating that glucose to go into the glycolycolic pathway itself, right? so as a result of that, glucose 6 -phosphate will be going to fructosex phosphate and then fructosex -phosphate to fructosex -phate and so on.
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If we observe these reactions that you observe, the glucose to glucose 1 -6 or the fructose 6 to fructose -1 -6 phosphate that you observe, some of them are irreversible.
01:34
Why are they reversible? like i said, to make sure that that product that is formed is going to go into the glycolytic pathway itself, right? so that is why some of them will be irreversible.
01:49
So we can say that some of the regulated metabolic pathways are irreversible.
01:55
Are they committed after the first step? yes, they are.
01:58
Are they regulated at the first step? yes, they are...