Question 42 Which of the following statements is true? a. Kinetochore proteins bind to the tubulin molecules at the minus end of microtubules. b. Sister chromatids are held together by condensins from the time they arise by DNA replication until the time they separate at anaphase. c. Microtubule-dependent motor proteins and microtubule polymerization and depolymerization are mainly responsible for the organized movements of chromosomes during mitosis. d. The centromere nucleates a radial array of microtubules called an aster, and its duplication is triggered by M-Cdk.
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Which of the following statements is true when thinking about chromosome movement? Microtubules attach to the kinetochores during early prophase. The microfilaments pull the chromosomes back and forth until they align in a plane along the equator of the cell, which is called the longitudinal plane. Astral microtubules attach to the chromosomes and move the chromatids. The kinetochore is composed of proteins that assemble on the centromere and provide a site for the microfilaments to attach. One mechanism for movement is the use of motor proteins kinesin and dynein by kinetochores.
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