Question

6 (6 points): Genes can be encoded on both strands of the DNA double-helix, and so it is possible to have genes arranged as diagrammed, with two transcription start sites nearby and with the genes leading in opposite directions. gene 1 gene 2 GAGCTATAAAGCTA promoter a) Briefly explain what you would expect the impact on transcription to be if the TATA box in the promoter of these genes contained a point mutation? b) Briefly describe the type of experiment a geneticist would conduct to identify whether that point mutation has the impact you predicted in part a. c) Which gene, if either, do you predict that the point mutation would impact the transcription of? Briefly explain your reasoning.

          6 (6 points): Genes can be encoded on both strands of the DNA double-helix, and so it is possible to have genes arranged as diagrammed, with two transcription start sites nearby and with the genes leading in opposite directions.

gene 1
gene 2
GAGCTATAAAGCTA
promoter

a) Briefly explain what you would expect the impact on transcription to be if the TATA box in the promoter of these genes contained a point mutation?
b) Briefly describe the type of experiment a geneticist would conduct to identify whether that point mutation has the impact you predicted in part a.
c) Which gene, if either, do you predict that the point mutation would impact the transcription of? Briefly explain your reasoning.

6 (6 points): Genes can be encoded on both strands of the DNA double-helix, and so it is possible to have genes arranged as diagrammed, with two transcription start sites nearby and with the genes leading in opposite directions.

gene 1
gene 2
GAGCTATAAAGCTA
promoter

a) Briefly explain what you would expect the impact on transcription to be if the TATA box in the promoter of these genes contained a point mutation?
b) Briefly describe the type of experiment a geneticist would conduct to identify whether that point mutation has the impact you predicted in part a.
c) Which gene, if either, do you predict that the point mutation would impact the transcription of? Briefly explain your reasoning.

Added by Francisco Javier F.

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