Question

7. (6 points) Retinoblastoma (Rb) is a rare cancer caused by a dominant autosomal allele with 90% penetrance. a) A man with Rb marries a normal woman with no family history of Rb. What is the chance that their first child will develop Rb? 3 points b) A phenotypically normal man whose mother had Rb marries a normal woman. What is the chance that their first child will develop Rb? (Think very carefully here!) 3 points

          7. (6 points) Retinoblastoma (Rb) is a rare cancer caused by a dominant autosomal
allele with 90% penetrance.
a) A man with Rb marries a normal woman with no family history of Rb. What is the
chance that their first child will develop Rb? 3 points
b) A phenotypically normal man whose mother had Rb marries a normal woman. What
is the chance that their first child will develop Rb? (Think very carefully here!) 3 points

7. (6 points) Retinoblastoma (Rb) is a rare cancer caused by a dominant autosomal
allele with 90% penetrance.
a) A man with Rb marries a normal woman with no family history of Rb. What is the
chance that their first child will develop Rb? 3 points
b) A phenotypically normal man whose mother had Rb marries a normal woman. What
is the chance that their first child will develop Rb? (Think very carefully here!) 3 points

Added by Eduardo T.

Biology for AP Courses

Julianne Zedalis, John Eggebrecht

Instant Answer

Solved by Expert Katlin Koehn

11/05/2022

Step 1

Step 1: For the first scenario, the man with Rb is heterozygous for the dominant allele (Rb/rr) and the normal woman is homozygous for the recessive allele (rr/rr). Show more…

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( 6 points) Retinoblastoma (Rb) is a rare cancer caused by a dominant autosomal allele with 90% penetrance. a) A man with Rb marries a normal woman with no family history of Rb. What is the chance that their first child will develop Rb ? 3 points b) A phenotypically normal man whose mother had Rb marries a normal woman. What is the chance that their first child will develop Rb ? (Think very carefully here!) 3 points 7.(6 points) Retinoblastoma (Rb) is a rare cancer caused by a dominant autosomal allele with 90% penetrance. a A man with Rb marries a normal woman with no family history of Rb. What is the chance that their first child will develop Rb?3 points b)A phenotypically normal man whose mother had Rb marries a normal woman.What is the chance that their first child will develop Rb?(Think very carefully here!)3 points