Question

A 32 year old pregnant woman is being seen at her wellness visit during her second pregnancy. She is blood type A, Rhesus negative. Her first baby was Rhesus positive. However, she did not receive RhoGham during her first pregnancy. As such, she has developed anit-D antibodies. Please address the following questions for this case study discussion. 1) what risk is there to the second baby knowing that the mother has developed anti-D antibodies during her first pregnancy? 2) Why do anti-D antibodies not fix complement? 3) Should the mother need a blood transfusion, should she receive Rhesus positive or Rhesus negative blood?

          A 32 year old pregnant woman is being seen at her wellness visit during her second pregnancy. She is blood type A, Rhesus negative. Her first baby was Rhesus positive. However, she did not receive RhoGham during her first pregnancy. As such, she has developed anit-D antibodies. Please address the following questions for this case study discussion. 
1) what risk is there to the second baby knowing that the mother has developed anti-D antibodies during her first pregnancy?
2) Why do anti-D antibodies not fix complement?
3) Should the mother need a blood transfusion, should she receive Rhesus positive or Rhesus negative blood?

Added by Stephen M.

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