A 32-year-old male, who is a nurse and has no psychiatric and neurological issues. Recently he undergoes genetic testing to know whether he carries a mutation in his Huntington Disease (HD) gene due to that his relatives from his mother side, including his mother, have clearly diagnosis with HD (you can search answer in your text book or search it online).
The test results for this 32-year-old male are:
HD allele 1: 16 repeats
HD allele 2: 44 repeats
What is the most accurate interpretation of this test:
This gentle man has HD and he should seriously consider different occupation because he will never be able to practice medicine.
He has one normal allele and mutant allele, he is a gene carrier and will never develop the disease.
Although he has inherited one HD gene mutation, given that he has no symptoms by the age of 32, he will never develop the disease.
This test result is inconclusive and thus his 50/50 risk of inheriting the disease from his mother
He is an asymptomatic individual who inherited an HD mutant allele and will develop symptoms of the disease if he gets older