A 5-year-old child was seen by her family physician because of weakness and headaches. She had been in good health except for the usual communicable diseases of childhood. Physical examination revealed a pale, listless child with multiple bruises. The WBC count was 15 x 10?/L, the haemoglobin was 8 g/dL, and the platelet count was 90 x 10?/L. She had ‘abnormal cells’ in her peripheral blood. A. What is the most likely diagnosis? B. What characteristics of this disease indicate a positive prognosis? Peripheral blood film for the patient in the case study (x1000).
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The most likely diagnosis based on the given information is leukemia, specifically acute lymphoblastic leukemia (ALL). The abnormal cells in the peripheral blood suggest the presence of leukemic blasts, which are immature white blood cells that are characteristic Show more…
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