00:01
Okay, i want to answer this question, let's talk about the electron trachechene.
00:03
Remember that if this is your inner mitochondrial membrane, okay? this is your inner mitochondrial membrane.
00:08
Let's draw it like this.
00:11
This is your inner mitochondrial membrane, and this is the outer mitochondrial.
00:14
And all of this is your mitochondrial.
00:19
So, if you're in the inner mitochondrial membrane, you're going to have the leadontran chain, this is complex number one, complex number two, complex number three, complex number four.
00:30
Okay? complex number one, for example, is called nadh dehydrogenase.
00:34
Hydrogenase and this one is called suzcinate dehydrogenase and this one is called cytocrine c or cytochrome b, i'm sorry, okay? so nadh is going to donate electrons here to complex number one and faadh is going to the same but in complex number two.
00:50
Then the molecule that is going to receive these electrons is coincide q.
00:55
This coinstein q is going to receive the electron for complex number one and two and it is going to take them to complex number three.
01:01
Then complex number three is going to give the electrons to cytocrine cytokrome b, sorry, cytokone c, and this cytokone c is going to deliver the electrons to complex number 4, where oxygen is going to accept those electrons.
01:13
Okay.
01:15
And the goal of all of this is to pump protons by complex number 1, by complex number 3, by complex number 4, in order to create a proton gradient here.
01:23
Okay, so you're going to have a higher concentration of protons here and a lower concentration of protons here.
01:29
So the only way by which these protons can move back to the matrix because of a gradient, they need to to come back to the matrix is by a transporter called atp synthics because this inner mitochondrial membrane is not permeable to these protons here and as this as this hydrogen ions move back to the protons to the matrix using this atp synthase this atp is going to undergo for correlation of an adp molecule to produce atp the question says um jeterate an anonymizing a causes electrons to become a stuck to use of here practically okay, because practically what actinomycin a does is that it is going to inhibit cytocrom c, or i'm sorry, cytokrome b, okay, or complex number 3.
02:17
So as it inhibits this complex number 3, then everything backwards is going to be inhibited.
02:22
Because remember that fadh, this complex number 2 is going to receive the electrons from fadh2 in order to become oxidized again, and this is going to go to the prep cycle, for example, in order to become again fadh2, and this is going to become a cycle...