A colon cancer screening study is being conducted in Nottingham, England. Individuals 50 to 75 years old will be screened with the Hemoccult test. In this test, a stool sample is tested for the presence of blood. The Hemoccult test has a sensitivity of 70% and a specificity of 75%. If the Hemoccult test result is positive, the individual will have a second stool sample test with Hemoccult II test with a sensitivity of 85% and specificity of 90%. Calculate the net sensitivity and specificity assuming that Nottingham has a prevalence of 12/1000 for colon cancer.
1. A colon cancer screening study is being conducted in
Nottingham, England. Individuals 50 to 75 years old
will be screened with the Hemoccult test. In this test, a
stool sample is tested for the presence of blood. The
Hemoccult test has a sensitivity of 70% and a
specificity of 75%. If the Hemoccult test result is
positive, the individual will have a second stool sample
test with Hemoccult Il test with a sensitivity of 85%
and specificity of 90%. Calculate the net sensitivity and
specificity assuming that Nottingham has a prevalence
of 12/1,000 for colon cancer.