1. Immune cells remain in tissues and do not circulate in the blood.
True / False
2. The ability of immune cells to disseminate throughout the body means that an immune response may be initiated at one site, but may be active at a distant location.
True / False
3. Leukocyte recruitment to sites of infection or injury is a major part of the process of inflammation.
4. Leukocyte homing refers to the delivery of myeloid cells from the bone marrow to the lymph nodes, where they mature.
5. After their arrival in peripheral lymphoid tissues, lymphocytes perform the following roles, with the exception of one. Which one is it?
a) Differentiate into effector lymphocytes
b) Recognize antigen
c) Return to the bone marrow where they instruct the formation of identical, antigen-specific lymphocytes
d) Proliferate
6. Naive lymphocytes permanently reside in a lymph node until they are activated by an antigen-presenting cell.
True / False
7. Prior to their adhesion to endothelial cells, leukocytes secrete chemokines.
True / False
8. Which of the following accurately describes the effect of cytokines (secreted by sentinel cells) on endothelial cells?
a) Decrease in the expression of adhesion molecules
b) Increase in the adhesiveness of the endothelial cells for circulating myeloid cells
c) Increase in the secretion of chemokine receptors
d) Increase in the adhesiveness of the endothelial cells for circulating naive lymphocytes
9. Selectins promote high-affinity adhesion to endothelial cells.
True / False
10. These selectins are found on the surface of endothelial cells.
a) L selectins
b) P selectins
c) E selectins
d) None of these selectins are found on endothelial cells