A glucose molecule (6 carbons) enters glycolysis, breaking down into two pyruvate molecules (3 carbons each) which then convert to acetyl-CoA (2 carbons each) through a transition reaction, entering the citric acid cycle (also known as the Krebs cycle) where the carbons are eventually released as CO2, with key intermediates including oxaloacetate and citrate; a fatty acid (variable number of carbons) undergoes beta-oxidation to generate acetyl-CoA molecules which then enter the citric acid cycle, ultimately releasing all carbons as CO2
Identify macronutrients that provide substrate to each pathway Map the cellular location of each pathway (e.g., cytosol, mitochondrial matrix) Detail if and how the pathways connect, identifying substrates that link pathways