Anti-B antibodies of a type A mother rarely affect the RBCs of a type B fetus. Yet anti-D antibodies of an Rh- woman sometimes cross the placenta and hemolyze the RBCs of an Rh+ fetus. Explain this difference based on your knowledge of the five immunoglobulin classes.
Added by James S.
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People with type A blood have A antigens on their RBCs, while those with type B blood have B antigens. Those with type AB blood have both A and B antigens, and those with type O blood have neither A nor B antigens. Now, when a person is exposed to an antigen that Show more…
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What is the blood type of someone whose blood creates agglutination with antibody A, antibody B and antibody D (Rh D)? What is the blood type of someone whose blood creates no agglutination with antibody A, antibody B and antibody D (Rh D)? List all the possible blood type combination that is compatible for someone with blood type AB-. Please provide explanation.
Adi S.
Complete the following statements about the role of Rh factor in hemolytic disease of newborns. Not all choices will be used. Blood type depends upon antigens as well as whether a person has or does not have Rh factor on the pathogens. If a fetus is Rh+ and its mother is Rh-, Rh- antibodies can leak across the placenta and cause the mother to produce anti-F Rh antibodies. In a subsequent pregnancy with an Rh+ child, the anti-Rh antibodies could cross the placenta and destroy the unborn child's RBCs. The baby will be severely anemic after birth, and hemolytic disease will continue.
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