00:01
Let us take a look at the given question.
00:02
So the question is basically based on the spindle assembly checkpoint.
00:06
So it is spindle assembly checkpoint.
00:15
So now let us understand first what is spindle assembly checkpoint.
00:20
So spindle assembly checkpoint is basically known as spindle checkpoint.
00:26
So it is also called as the metaphase checkpoint.
00:31
So meta phase checkpoint.
00:33
Now it is a cell cycle checkpoint during mitosis or meiosis that prevents the separation of duplicated chromosomes.
00:48
So it prevents the separation of duplicated chromosomes.
01:09
It prevents the separation of duplicated chromosomes until each chromosome is properly attached to the spindle.
01:16
Until each chromosome is properly attached to the spindle.
01:38
So basically here what happened is like to achieve the proper segregation, the two kinetor codes on the sister chromatates must be attached to opposite spindle poles.
01:50
So the defining biochemical feature of this checkpoint is the stimulation of anaphis promoting complex.
01:56
So it stimulates anaphase promoting complex.
02:08
Promoting complex, that is apc, enophase promoting complex by m phase, by m phase ciclin cdk complexes...