A mutation occurs in the promoter region of a gene. Which of the following is the most likely effect this mutation would have on gene expression? Group of answer choices It will alter the amino acid sequence of the encoded protein. It will prevent proper splicing of the pre-mRNA. It will decrease the stability of the mRNA during translation. It will affect the initiation of transcription, potentially reducing or eliminating gene expression
Added by Michael P.
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Step 1: Identify the role of the promoter region – it is where RNA polymerase binds and transcription is initiated. Show more…
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What would be the most likely effect of a mutation in the promoter of a gene? You can assume that this mutation does not affect the position of the transcription start site. Expression of the gene may change, but the resulting RNA and protein sequences will not be changed The sequence of the protein made from the gene will be changed Translation will not begin, since the AUG stop codon will likely be changed Splicing of the mRNA will occur at a different position The expression of the gene will NOT change, but the RNA made from the gene will have a different sequence What provides the energy for the formation of an RNA transcript? RNA polymerase hydrolyzes one molecule of ATP EACH time it adds a nucleotide Building a polymer out of monomers increases the entropy of the system A nucleotide is phosphorylated when it is added to a chain of ribonucleotides The building blocks of RNA (ribonucleoside triphosphates) provide the energy RNA polymerase increases the free energy of the reactants What would be the effect of removing the 5' cap of an mRNA transcript? Transcription would not be initiated Introns would remain a part of a mature mRNA transcript The poly(A) tail of the transcript would get longer The transcript would be less likely to be translated Which of the following will be ultimately affected by alternative splicing? Only the DNA sequence of the gene Only the mature mRNA sequence of the gene Only the protein made from the gene Both the mature mRNA and protein sequences The DNA, RNA, and protein sequences are all altered by splicing.
Sri K.
Suppose a mutation happened within a gene's enhancer region. What effect would this be most likely to have on the expression of the gene? a. It could create a start codon b. It could change one amino acid to a different one c. It could affect whether transcription happened or not d. It could create a stop codon e. It could create a frameshift mutation
Adi S.
Which of the following are likely effects of a promoter mutation? Loss of gene transcription Altered protein function due to an altered amino acid sequence in the translated protein Promoter mutations do not alter gene expression, because promoters are not part of a gene's region that gets transcribed into RNA Gain of expression in the "wrong" cells Altered protein function due to changes in protein structure, caused in turn by changes in protein abundance
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