A mutation that prevents the dissociation of the lac repressor from the operator.
Added by Troy P.
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The lac repressor binds to the operator region of the lac operon, preventing transcription of genes involved in lactose metabolism when lactose is not present. Show more…
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There is a mutation in the lacI regulatory gene that results in the generation of a super-repressor protein, which represses the lac operon permanently. Which of the following describes this mutant super-repressor protein? Select one alternative: It cannot bind to the operator. It binds to the cAMP receptor protein (CAP) permanently. It binds to a site at the far end of the operon, past the transacetylase (lacA) gene. It binds to the operator regardless of whether lactose is present.
Aparna S.
What would be the consequence of a mutation in the lacI repressor gene that produces repressor protein that is able to bind to the operator but is not able to bind allolactose?
Nicholas M.
Suppose you discover a mutation in the lac repressor that results in a molecule known as a super-repressor because it represses the lac operon permanently. Which of these statements would characterize the lac repressor in such a mutant? It cannot bind to the ligand (inducer). It cannot bind to the operator DNA. It cannot bind to the RNA polymerase. It cannot bind to the ribosome. The mutation causes a change in the protein structure of the repressor, which leads to denaturation and precipitation.
Marlyn J.
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