A neutral mutation occurs in a monomorphic wild-type population of size 5000 individuals, such that in the next generation there is one mutant. The effective population size of this population is 1000. Assuming that no other mutations occur in the near future, what is the probability that this new neutral mutant will fix in the population?
If Āµ = 10ā»āø is the per-site per-generation mutation rate of a malaria parasite, and if the malaria genome has a total size of 23 million base pairs, how many mutations do you expect to occur in one individual parasite generation of replication?