A particular globular protein forms a homodimer (a dimer of two identical subunits). Predict where most nonpolar amino acids will be located in the three-dimensional structure of the dimer. Nonpolar amino acids will be evenly distributed in three-dimensional space. Nonpolar amino acids will be located everywhere except at the interface between subunits in the dimer. Nonpolar amino acids will be located on the interior of the globular subunits and at the interface between subunits in the dimer. Nonpolar amino acids will be located on the interior of the globular subunits.
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Step 1: Restate the problem — we must predict where most nonpolar (hydrophobic) amino acids will be located in the 3D structure of a homodimeric globular protein. Show more…
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In general, proteins fold so that: - Polar groups are found primarily on the surface of the protein. - Nonpolar groups lie next to polar groups. - Nonpolar groups are found primarily on the surface of the protein. - Polar groups are found primarily in the interior of the protein.
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