1. A pedigree is shown below for a common dimorphism with full penetrance and expressivity. Please fill in the correct genotypes on the lines shown in the pedigree. The lines are below the person for which you need to provide a genotype. Use gene symbols A and a. If an allele can not be determined, use a dash (-). If a genotype is highly likely for (an) individual(s), show the highly likely genotype(s) and explain your reasoning. It is recommended that you print extra copies to work with and then upload the clean, final copy. This way you can work through the problem with care and the grader will not be confused by your gene symbols. genotype
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Since the trait is fully penetrant and expressive, we can assume that individuals with the trait are homozygous recessive (aa) and individuals without the trait are either homozygous dominant (AA) or heterozygous (Aa). Show more…
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15. Use the following pedigree to answer the following questions. (i) How many generations are shown in this pedigree? (ii) How many women have the disease in this pedigree? (iii) Does this pedigree show an autosomal recessive disease or an autosomal dominant disease? Explain your answer! (iii) What are the genotypes for all of the individuals on this pedigree? Write them on the line underneath each individual. Hint: What must the genotypes of unaffected individuals be? From there, use Punnett squares to help you determine the rest of the genotypes (use the space below if you need it for the Punnett squares)!
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Genotype Genotype Genotype Genotype The FIRST time you draw this pedigree, you will assume the trait is autosomal dominant. Use the alleles "A" and "a" to figure out what everyone's genotype is. The SECOND time you draw this pedigree, you will assume the trait is autosomal recessive. Using a new, clean drawing, and starting from scratch, write in the alleles "A" and "a" for the trait being inherited in an autosomal recessive patter. The THIRD time you draw this pedigree, you will assume the trait is X-linked Dominant. Use the chromosomes X^A and X^a and Y (remember, males are XY and females are XX) to show everyone's genotype and sex chromosomes. The FOURTH time you draw this pedigree, you will assume the trait is X-linked Recessive. Use the chromosomes X^A and X^a and Y to show everyone's genotype and sex chromosomes.
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