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a pedigree of a family with a rare genetic disorder is shown 

          a pedigree of a family with a rare genetic disorder is shown

Added by Mary K.

Biology for AP Courses
Biology for AP Courses
Julianne Zedalis, John Eggebrecht
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a pedigree of a family with a rare genetic disorder is shown
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The pedigree shown below demonstrates a disorder that is inherited as a ___ disorder. Assume the trait is rare in the population and that, excluding the first generation, any individual marrying into the family is not a carrier. Y linked autosomal dominant X linked recessive autosomal recessive X linked dominant

Katlin K.
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Transcript

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00:01 Hi, the given question from rare human autosomal recessive inheritance, or we can say that disease.
00:23 So, in autosomal recessive inheritance, most likely explanation when individuals are affected in a single generation or there is a concern.
00:57 Sanguinity of the patient is of an ethnicity with high frequency of carrier of a condition.
01:08 And some examples are like tysatz disease is the example.
01:27 Generally autosomal recessive disease in this disease.
01:42 Parents are generally in this disease parents of the affected child may be clinically normal or we can say that that is carrier next that is assuming that carrier frequency in the population is low only siblings are affected are affected and vertical transmission vertical transmission does not occur pattern therefore tend to appear horizontally also male and females affected the equal proportion and the when both parents lastly parents both parents are heterogamous carrier of the mutation, that is 25 % of their child affected...
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