A series of enzymes catalyze the reaction X -> Y -> Z -> A. Product A binds to the enzyme that c

Name: A series of enzymes catalyze the reaction X -> Y -> Z -> A. Product A binds to the enzyme that converts X to Y at a position remote from its active site. This binding decreases the activity of the enzyme. With regards to the enzyme that converts X to Y, substance A functions as: the substrate a competitive inhibitor an intermediate an allosteric inhibitor
Uploaded: 2022-01-28T16:28:23-08:00
Duration: 4 min 46 s
Channel: Shakti R
Description: A series of enzymes catalyze the reaction X -> Y -> Z -> A. Product A binds to the enzyme that converts X to Y at a position remote from its active site. This binding decreases the activity of the enzyme. With regards to the enzyme that converts X to Y, substance A functions as: the substrate a competitive inhibitor an intermediate an allosteric inhibitor

First, substance A is not the substrate because the substrate in this reaction is X, which is co

A series of enzymes catalyze the reaction X -> Y -> Z -> A....

A series of enzymes catalyze the reaction X -> Y -> Z -> A. Product A binds to the enzyme that converts X to Y at a position remote from its active site. This binding decreases the activity of the enzyme. With regards to the enzyme that converts X to Y, substance A functions as: the substrate a competitive inhibitor an intermediate an allosteric inhibitor

Transcript

00:01 So here the series of enzyme catalyze reactions are given and that series of reactions which is catalyzed by enzyme that is x is converted to y then y is converted to the z and z is converted ultimately to the a.

00:17 And here the a is considered as the product of the pathway or the series of reactions and here the enzyme catalyzing this first step or first chemical reaction that is enzyme 1 that we assume here the enzyme 2 and enzyme 3 which is catalyzing this y to z and z to a reactions now here the given data says that the a or the product here that is inhibiting the first enzyme that catalyze the reaction of x to y conversion so ultimately this is the inhibiting so generally this kind of reaction or reggae mechanism happens when this product is in excess amount.

01:06 That's why this product will inhibit the first enzyme.

01:10 So in this case the product inhibits the first enzyme of the reactions and then we can easily stop the first reaction that is x to y and ultimately we can reduce the production of this final product and this mechanism is known as the feedback inhibition that is the final product can inhibit the whole pathway now let us look at how the a product is inhibiting the first enzyme so as we have already seen the structure of enzymes enzymes are the biomolecules or ultimately they are the proteins and enzymes have two crucial sites the very first site is known as the active side enzymes have two main sites the first is active side and some enzymes also have the allosteric side okay now that at active side the substrate will bind and at the elosteric side of the enzyme the activator or the inhibitor molecule binds okay now as this is the active site and as we consider this as the allosteric side.

02:38 Okay, now at this allosteric side, the a molecule binds.

02:47 Okay, so this a molecule which is bind at the allosteric side of the enzyme and ultimately it will act as the inhibitor.

02:56 So here, this is the inhibitor for the enzyme one.

03:01 This kind of inhibition is known as allosteric inhibition as it is inhibited by the elosteric inhibitor which binds with the enzyme.

03:10 So this inhibitor will inhibits or it will decrease the enzyme one activity or the activity of enzyme.

03:23 So here the question is that the a functions as what? so a is functioning as what? it is very much clear now that a is functioning as the inhibitor.

03:33 Or we can say the elosteric inhibitor...

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