a. Why can't glycolysis simply be run in reverse to synthesize glucose? Detail the three irreversible steps in glycolysis and how those steps are altered in gluconeogenesis. Be sure to include enzyme names and intermediate molecules when necessary. b. Detail at least two differences in the synthesis of the leading strand and the lagging strand in DNA replication.
Added by Tracy K.
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Glycolysis cannot simply be run in reverse to synthesize glucose because there are three irreversible steps in glycolysis that require different enzymes and reactions in gluconeogenesis. These steps are: Show more…
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Gluconeogenesis is the reverse process of glycolysis, but it is not exactly the reverse. - Why is gluconeogenesis NOT just glycolysis running in reverse? Why can't glycolysis just be run in reverse? - What is the energetic "cost" of gluconeogenesis? - List the four reactions that are different between glycolysis and gluconeogenesis.
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