Achondroplasia is a common cause of dwarfism in humans. All individuals with achondroplasia are thought to be heterozygous at the locus that controls this trait. When two individuals with achondroplasia mate, the offspring occur in a ratio of 2 achondroplasia:1 normal. What is the most likely explanation for these observations? The allele that causes achondroplasia is a dominant lethal allele. Achondroplasia is codominant to the normal condition. The allele that causes achondroplasia is a recessive lethal allele. The allele that causes achondroplasia is a late-onset lethal allele. Achondroplasia is incompletely dominant to the normal condition.
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If achondroplasia was a recessive trait, then both parents would need to be homozygous recessive (aa) to have the condition. However, this would result in all offspring also being homozygous recessive (aa) and having achondroplasia, which does not match the given Show more…
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Achondroplasia is a form of dwarfism in humans. It is caused by a mutant allele of the fibroblast growth factor receptor (FGFR) gene that produces an overactive protein. Having one copy of the mutant allele results in dwarfism. Having two copies of the mutant allele results in stillbirth (infant dies in the womb). Which allele, the mutant allele or the wild-type allele, is recessive with respect to viability? Mutant allele Wild-type allele
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Achondroplasia is a common cause of dwarfism in humans. All individuals with achondroplasia are thought to be heterozygous at the locus that controls this trait. When two individuals with achondroplasia mate, the offspring occur in a ratio of 2 achondroplasia : 1 normal. What is the MOST likely explanation for these observations? Achondroplasia is codominant to the normal condition. The allele that causes achondroplasia is a recessive lethal allele. The allele that causes achondroplasia is a dominant lethal allele. The allele that causes achondroplasia is a late-onset lethal allele. Achondroplasia is incompletely dominant to the normal condition.
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