Africa Sleeping Sickness is caused by a single celled parasite, Trypanosoma, that infects our blood cells and liver. This parasite has proven difficult to immunize people against with most vaccinations proving unsuccessful. Examine the graph below showing infection concentrations of the parasite over time in the blood of an infected person along with the percent production of certain antibodies displayed on the second y-axis (on the right side). Propose a hypothesis and explanation for why many vaccines have been unsuccessful in immunizing people against the pathogen. Can you think of a genetic mechanism Trypanosoma has for being a "good" parasite?
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