Question

After a search of nucleotide sequence databases, researchers identified an IRE in the 5' untranslated region of a gene encoding aconitase, an enzyme involved in the Krebs cycle. Which of the following pieces of experimental evidence best supports the claim that the synthesis of aconitase is controlled by mechanism similar to ferritin regulation? (A) IRP binds to aconitase mRNA in the presence of iron. (B) The relative amount of aconitase protein increases in the presence of high levels of iron. (C) Oxygen consumption by cells increases in the presence of high levels of iron. (D) The levels of reduced electron carriers, NADH and FADH2, increase in the presence of high levels of iron.

          After a search of nucleotide sequence databases, researchers identified an IRE in the 5' untranslated region of a gene encoding aconitase, an enzyme involved in the Krebs cycle. Which of the following pieces of experimental evidence best supports the claim that the synthesis of aconitase is controlled by mechanism similar to ferritin regulation?
(A) IRP binds to aconitase mRNA in the presence of iron.
(B) The relative amount of aconitase protein increases in the presence of high levels of iron.
(C) Oxygen consumption by cells increases in the presence of high levels of iron.
(D) The levels of reduced electron carriers, NADH and FADH2, increase in the presence of high levels of iron.

After a search of nucleotide sequence databases, researchers identified an IRE in the 5' untranslated region of a gene encoding aconitase, an enzyme involved in the Krebs cycle. Which of the following pieces of experimental evidence best supports the claim that the synthesis of aconitase is controlled by mechanism similar to ferritin regulation?
(A) IRP binds to aconitase mRNA in the presence of iron.
(B) The relative amount of aconitase protein increases in the presence of high levels of iron.
(C) Oxygen consumption by cells increases in the presence of high levels of iron.
(D) The levels of reduced electron carriers, NADH and FADH2, increase in the presence of high levels of iron.

Added by Jesse G.

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