After containment of an injury, the tissue repair phase starts with removal of toxins and waste products. Clotting (coagulation) blank 1 blood loss from damaged blood vessels and forms a network of fibrin proteins that trap blood cells and bind the edges of the wound together. A blank 2 forms when the clot dries, reducing the risk of infection. Sometimes a mixture of dead leukocytes and fluid called pus accumulates in the wound. As healing progresses, blank 3 from the surrounding connective tissues replace the collagen and extracellular material lost by the injury. Blank 4, the growth of new blood vessels, results in vascularization of the new tissue known as blank 5 tissue. The clot retracts pulling the edges of the wound together, and it slowly dissolves as the tissue is repaired. When a large amount of granulation tissue forms and capillaries disappear, a pale scar is often visible in the healed area. A blank 6 describes the healing of a wound where the edges are close together. When there is a gaping wound, it takes longer to refill the area with cells and collagen. The process called blank 7 occurs as the edges of the wound are pulled together by what is called blank 8. When a wound is more than one quarter of an inch deep, sutures (stitches) are recommended to promote a primary union and avoid the formation of a disfiguring scar. Blank 9 is the addition of new cells of the same type as the ones that were injured.
In blank 10, a new type of tissue develops, which eventually produces a scar and causes the loss of some tissue function. Most wounds heal through regeneration and replacement; which process dominates depends on the tissues involved and the nature and extent of the wound.