An apparently healthy 24-year-old basket ball player dies suddenly during the game, when Aorta, the largest artery ruptures. A younger brother a nearsighted and has long and thin fingers and older sister extremely fall with long arms and legs. The older sister too has weakened aorta. All these have Marfan Syndrome
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What is Marfan Syndrome? Marfan Syndrome is a genetic disorder that affects the connective tissue in the body. Connective tissue provides support and structure to various organs and tissues in the body, including the heart, blood vessels, bones, and eyes. People Show more…
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Marfan's syndrome is a disorder of the fibrous connective tissue, characterized by many symptoms, including long, thin digits; eye defects; heart disease; and long limbs. (Flo Hyman, the American volleyball star, suffered from Marfan's syndrome. She died from a ruptured aorta.) a. Use the pedigree above to propose a mode of inheritance for Marfan's syndrome. b. What genetic phenomenon is shown by this pedigree? c. Speculate on a reason for such a phenomenon. (Data from J. V. Neel and W. J. Schull, Human Heredity. University of Chicago Press, $1954 .$
A 12 year-old boy fell while playing basketball. The physician explained that the head (epiphysis) of the femur was separated from the shaft (diaphysis). Although the bone was properly set, by the time the boy was 16 it was apparent that the injured lower limb was shorter than the normal one. Explain why this difference occurred.
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