An experimental drug is being developed to selectively inhibit
TH cells to prevent organ rejection. How will this help
patients?
When TH cells are inhibited, macrophages become less phagocytic
and will not attack the donated organ.
By inhibiting TH cells, B cells will be able to proliferate
extensively, allowing them to protect the donated organ from
rejection.
Inhibiting TH cells will reduce the number of phagocytic TH
cells in the blood which in turn will do less damage on the donated
organ.
If TH cells are inhibited, TC cells fail to become active and
will do less damage to the cells of the donated organ. If TH cells
are inhibited, TC cells fail to become active and will do less
damage to the cells of the donated organ.